-end. Efficient replication occurs in primary erythrocyte precursors. There have also been reports of productive infection of primary umbilical cord erythrocytes and of a continuous line of megakaryoblastoid cells.
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Type Species |
(B19V) |
Populations of mature virions contain equivalent numbers of positive and negative sense ssDNA, 5 kb in size. The DNA molecules contain inverted terminal repeats of 383 nts, the first 365 nts of which form a palindromic sequence. Upon extraction, the complementary DNA strands usually form dsDNA. There is a single mRNA promoter (map unit 6) and two polyadenylation signals, one near the middle of the genome, the other near the 3-end. Efficient replication occurs in primary erythrocyte precursors. There have also been reports of productive infection of primary umbilical cord erythrocytes and of a continuous line of megakaryoblastoid cells.
Official virus species names are in italics. Tentative virus species names, alternative names ( ), strains or serotypes are not italicized. Virus name, genome sequence accession numbers [ ], and assigned abbreviation ( ) are:
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B19 virus |
[M13178, M24682] |
(B19V) |
Tentative species in the Genus
None reported.
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