DESCRIPTION OF VIRUSES

Family Caliciviridae

Genus “Sapporo-Like Viruses”

Genus “Sapporo-Like Viruses”

Type Species

Sapporo virus

(SV)

Distinguishing Features

The strains in this genus form a distinct phylogenetic clade within the family. The full-length genomic sequence is available only for the Manchester virus. The Manchester virus genome is organized into three major ORFs. ORF1 encodes the non-structural polyprotein, with the major structural CP gene in frame with the nonstructural polyprotein coding sequence. ORF2 overlaps the ORF1 in a-1 frameshift and encodes a predicted small protein of unknown function. ORF3 begins 11  nts downstream from the predicted start codon of the CP in a+1 frameshift and encodes a predicted protein of approximately 160 amino acids. However, in certain strains of this genus, ORF3 is absent. The viruses in this genus have characteristically been associated with sporadic outbreaks and cases of gastroenteritis in humans and often (but not always) have distinct calicivirus cup-like morphology when observed by negative stain electron microscopy.

List of Species Demarcation Criteria in the Genus

Not applicable. Additional characterization of the viruses in this genus will be required in order to delineate species criteria.

List of Species in the Genus

Official virus species names are in italics. Tentative virus species names, alternative names ( ), strains or serotypes are not italicized. Virus names, genome sequence accession numbers [ ], and assigned abbreviations ( ) are:

Species in The Genus

Sapporo virus

(SV)

Houston/86

[U95643]

(Hu/SV/Hou/1986/US)

Houston/90

[U95644]

(Hu/SV/Hou 27/1990/US)

London 29845

[U95645]

(Hu/SV/Lon 29845/1992/UK)

Manchester virus

[X86560]

(Hu/SV/Man/1993/UK)

Parkville virus

[U73124]

(Hu/SV/Park/1994/US)

Sapporo virus

[U65427]

(Hu/SV/SV/1982/JA)

Tentative Species in the Genus

None reported.


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