|
Type Species |
(NV) |
The strains in this genus form a distinct phylogenetic clade within the family. The genome is organized into three major ORFs. ORF1 encodes the nonstructural polyprotein. ORF2 encodes the major structural CP and overlaps by 14 nts with the ORF1 in the Norwalk and Southampton virus strains and by 17 nts in the Lordsdale virus strain, resulting in a-2 frameshift of the ORF2 in all three viruses. ORF3 overlaps by one nt with the ORF2 in a-1 frameshift and encodes a small protein of unknown function. Members of the genus often (but not always) have a less-defined surface structure when observed by negative stain electron microscopy, leading to the now historic descriptive term “small round structured viruses” for the viruses in this genus associated with epidemic gastroenteritis in humans.
List of Species Demarcation Criteria in the Genus
Not applicable. Additional characterization of the viruses in this genus will be required in order to delineate species criteria.
Official virus species names are in italics. Tentative virus species names, alternative names ( ), strains or serotypes are not italicized. Virus names, genome sequence accession numbers [ ], and assigned abbreviations ( ) are:
|
Norwalk virus |
(NV) | |
|
Desert Shield virus |
[U04469] |
(Hu/NV/DSV395/1990/SR) |
|
Hawaii virus |
[U07611] |
(Hu/NV/HV/1971/US) |
|
Lordsdale virus |
[X86557] |
(Hu/NV/LD/1993/UK) |
|
Mexico virus |
[U22498] |
(Hu/NV/MX/1989/MX) |
|
Norwalk virus |
[M87661] |
(Hu/NV/NV/1968/US) |
|
Snow Mountain virus |
[L23831] |
(Hu/NV/SMV/1976/US) |
|
Southampton virus |
[L07418] |
(Hu/NV/SHV/1991/UK) |
Tentative Species in the Genus
|
Swine calicivirus |
[AB009412] |
(Sw/NV/Sw43/1997/JA) |
|
| |