A major phylogenetic branch within the genus,
A common genome layout,
Greater than 80% amino acid identity in the CP,
A natural host range,
Cross-protection antigens.
|
Type Species |
(RHDV) |
The strains in this genus form a distinct phylogenetic clade within the family. The genome is organized into two major ORFs. ORF1 encodes the nonstructural polyprotein, with the major structural CP gene (VP60) in frame with the nonstructural polyprotein coding sequence. ORF2 overlaps the ORF1 by 17 nts in the RHDV genome and 5 nts in the EBHSV genome. The ORF2 encodes a small protein (VP10) of unknown function that has been identified as a minor structural component in the RHDV virion. These viruses have characteristically been associated with infection in rabbits and hares (lagomorphs), and can cause epidemics with high mortality in these animals.
List of Species Demarcation Criteria in the Genus
Members of a Lagovirus species share:
|
A major phylogenetic branch within the genus, |
|
A common genome layout, |
|
Greater than 80% amino acid identity in the CP, |
|
A natural host range, |
|
Cross-protection antigens. |
Official virus species names are in italics. Tentative virus species names, alternative names ( ), strains or serotypes are not italicized. Virus names, genome sequence accession numbers [ ], and assigned abbreviations ( ) are:
|
European brown hare syndrome virus |
(EBHSV) | |
|
EBHSV-BS89 |
[X98002] |
(Ha/LV/EBHSV/BS89/1989/IT) |
|
EBHSV-FRG |
[U09199] |
(Ha/LV/EBHSV/FRG/1989/GE) |
|
EBHSV-GD |
[Z69620] |
(Ha/LV/EBHSV/GD/1989/FR) |
|
EBHSV-UK91 |
[U65372] |
(Ha/LV/EBHSV/UK91/1991/UK) |
|
Rabbit hemorrhagic disease virus |
(RHDV) | |
|
Rabbit calicivirus |
[X96868] |
(Ra/LV/RHDV/RCV/1995/IT) |
|
RHDV-AST89 |
[Z49271] |
(Ra/LV/RHDV/AST89/1989/SP) |
|
RHDV-BS89 |
[X87607] |
(Ra/LV/RHDV/BS89/1989/IT) |
|
RHDV-FRG |
[M67473] |
(Ra/LV/RHDV/GH/1988/GE) |
|
RHDV-SD |
[Z29514] |
(Ra/LV/RHDV/SD/1989/FR) |
|
RHDV-V351 |
[U54983] |
(Ra/LV/RHDV/V351/1987/CK) |
Tentative Species in the Genus
None reported.
|
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