Figure 1 (Left) Diagram illustrating rhabdovirus virion and nucleocapsid structure (Courtesy of P. Le Mercier); (Right) Negative contrast electron micrograph of Vesicular stomatitis Indiana virus (VSIV) particles (Courtesy of P. Perrin). The bar represents 100 nm.
Figure 2 In (1) is shown the gene organization for Vesicular stomatitis Indiana virus (VSIV) and the process of consecutive transcription of leader RNA and monocistronic mRNAs; in (2), is shown the replication of the negative sense genome via a positive sense antigenome intermediate. The switch from transcription to replication appears to be regulated by the N protein. (Courtesy of P. Le Mercier.)
Figure 3 Phylogenetic relationships between rhabdoviruses based on a GDE alignment of a relatively conserved region of the N protein (119 amino acids), and using the paramyxovirus Human parainfluenza virus 1 (HPIV-1) as the outgroup. The tree was generated by the neighbor-joining method and bootstrap values (indicated for each branch node) were estimated using 1000 tree replicas. Branch lengths are proportional to genetic distances. The scale bar corresponds to substitutions per amino acid site. (Courtesy of H. Badrane and P.J. Walker.)
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