Table 1 Marburg virus (MARV) and Zaire Ebola virus (ZEBOV) structural proteins.
|
Marburg virus |
Zaire Ebola virus | |||
|
Protein |
Encoding gene |
Function |
Mr ( 103) A/B |
Mr ( 103) A/B |
|
NP |
1 |
nucleoprotein |
77.9 / 96.0 |
83.3 / 104.0 |
|
VP35 |
2 |
phosphoprotein |
31.0 / 32.0 |
38.8 / 35.0 |
|
VP40 |
3 |
matrix protein |
31.7 / 38.0 |
35.3 / 40.0 |
|
GP |
4 |
glycoprotein |
74.8 / 170.0 |
74.5 / 140.0 |
|
VP30 |
5 |
nucleoprotein (?) |
31.5 / 28.0 |
29.7 / 30.0 |
|
VP24 |
6 |
matrix protein (?) |
28.8 / 24.0 |
28.3 / 24.0 |
|
L |
7 |
polymerase/replicase |
267.2 / >200.0 |
252.7/ >200.0 |
Mr/A, molecular ratio calculated from the deduced amino acid sequences of the corresponding ORFs. Mrr/B, molecular ratio estimated from SDS-PAGE analysis.
Table 2 Amino acid homologies of surface glycoproteins of different representatives of the family Filoviridae, made from alignments of different Ebola virus and one Marburg virus strains.
|
Species |
REBOV |
SEBOV |
CIEBOV |
ZEBOV |
ZEBOV |
ZEBOV |
MARV |
|
Strains |
Reston-89 |
Boniface 76 |
Tai Forest 94 |
Gabon-94 |
Zaire-76 |
Zaire-95 |
Musoke 80 |
|
Reston-89 |
100 |
60.8 |
58.7 |
58.7 |
58.8 |
58.8 |
29.6 |
|
Boniface 76 |
100 |
56.6 |
56.4 |
55.8 |
56.4 |
30.5 | |
|
Tai Forest 94 |
100 |
66.0 |
65.9 |
66.2 |
30.2 | ||
|
Gabon-94 |
100 |
97.9 |
99.1 |
30.9 | |||
|
Zaire-76 |
100 |
98.5 |
31.1 | ||||
|
Zaire-95 |
100 |
30.8 | |||||
|
Musoke-80 |
100 |
|
|