DESCRIPTION OF VIRUSES

Family Herpesviridae

Genus Lymphocryptovirus

Genus Lymphocryptovirus

Type Species

Human herpesvirus 4

(HHV-4)

Distinguishing Features

The nucleotide or predicted amino acid sequences of members of the genus form a distinct lineage within the subfamily. The EBNA genes of HHV-4 and their homologues appear to be unique to members of the genus. The viruses infect B-lymphocytes in culture but infection is usually non-productive and can result in immortalisation. B cells or their precursors are thought to be the site of latent infection in vivo. Current members of the genus have been found only in human or non-human primates and all members of the genus are serologically related.

List of Species Demarcation Criteria in the Genus

See above under “List of Species Demarcation Criteria in the Family“.

List of Species in the Genus

Official virus species names are in italics. Tentative virus species names, alternative names ( ), strains or serotypes are not italicized. Virus names, genome sequence accession numbers [ ], and assigned abbreviations ( ) are:

Species in the Genus

Cercopithecine herpesvirus 12

(CeHV-12)

(Herpesvirus papio)

(Baboon herpesvirus)

Cercopithecine herpesvirus 14

(CeHV-14)

(African green monkey EBV-like virus)

Cercopithecine herpesvirus 15

(CeHV-15)

(Rhesus EBV-like herpesvirus)

Human herpesvirus 4

[G59074]

(HHV-4)

(Epstein-Barr virus)

Pongine herpesvirus 1

(PoHV-1)

(Herpesvirus pan)

Pongine herpesvirus 2

(PoHV-2)

(Orangutan herpesvirus)

Pongine herpesvirus 3

(PoHV-3)

(Gorilla herpesvirus)

Tentative Species in the Genus

None reported.