Genus Simplexvirus

Type Species	Human herpesvirus 1	(HHV-1)

Distinguishing Features

Nucleotide sequences or predicted amino acid sequences of members of the genus form a distinct lineage within the subfamily. The viruses have a broad host cell range in vitro with a relatively rapid cytolytic productive cycle. Latent infection is established in neurones. Most members of the genus are viruses of human or non-human primates. Members of the genus may have serological cross-reaction with other members.

List of Species Demarcation Criteria in the Genus

See above under “List of Species Demarcation Criteria in the Family“.

List of Species in the Genus

Official virus species names are in italics. Tentative virus species names, alternative names ( ), strains or serotypes are not italicized. Virus names, genome sequence accession numbers [ ], and assigned abbreviations ( ) are:

Species in the Genus

Ateline herpesvirus 1		(AtHV-1)
(Spider monkey herpesvirus)
Bovine herpesvirus 2		(BoHV-2)
(Bovine mamillitis virus)
Cercopithecine herpesvirus 1		(CeHV-1)
(B-virus; Herpesvirus simiae)
Cercopithecine herpesvirus 2		(CeHV-2)
(SA8)
Cercopithecine herpesvirus 161		(CeHV-16)
(Herpesvirus papio 2)
Human herpesvirus 1	[X14112]	(HHV-1)
(Herpes simplex virus 1)
Human herpesvirus 2	[Z86099]	(HHV-2)
(Herpes simplex virus 2)
Saimiriine herpesvirus 1		(SaHV-1)
(Herpesvirus tamarinus)
(Marmoset herpesvirus)

¹ (Eberle, Black, Lipper and Hilliard, 1995)

Tentative Species in the Genus

None reported.