DESCRIPTION OF VIRUSES

Family Poxviridae

Subfamily Chordopoxvirinae

Subfamily Chordopoxvirinae

Taxonomic Structure of the Subfamily

Subfamily

Chordopoxvirinae

    Orthopoxvirus

    Parapoxvirus

    Avipoxvirus

    Capripoxvirus

    Leporipoxvirus

    Suipoxvirus

    Molluscipoxvirus

    Yatapoxvirus

Distinguishing Features

Includes brick-shaped or ovoid poxviruses of vertebrates with a low G+C content (30-40%), except for the parapoxviruses (64%) and Molluscum contagiosum virus (63%). Extensive serologic cross-reaction and cross-protection is observed within genera, this is less obvious among the avipoxviruses. A common, conserved co-linear signature core of genes within genera (and in the case of mammalian viruses, spanning genera) is generally maintained with most divergence amongst members occurring at the terminal extremes of the genome. The co-linear signature of core genes appears different for mammalian, avian and insect poxvirus genera. Some viruses produce pocks on the chorioallantoic membranes of embryonated chicken eggs.